Metabolic and Nutrition Phenotyping in NSCI
Body Composition, Bone Mineral Density, and Trace Element Analysis
The Department of Nutritional Sciences Core Facility houses equipment available for use (with user fees) to researchers across OSU campuses.
Equipment Usage Fee Structure
Hologic Discovery A QDR 4500 Series Dual-energy X-ray Absorptiometers (DXA):) DXA is the industry standard for measuring both human and animal bone density, but
is also a valuable tool for assessing body composition (lean body mass and adipose).
Currently, the Department of Nutritional Sciences houses two state-of-the-art Hologic
DXA’s (same model, however, one with a 300 lb. weight limit; the newer one with a
450 lb. weight limit) which are utilized by researchers in the department, in addition
to other departments on campus, to determine the effects of dietary and environmental
factors on bone mineral density.
Faculty Contacts: Drs. Brenda Smith and Edralin Lucas
Scanco Medical mCT 40: This mCT unit is designed to scan small bone specimens (i.e., rodent or larger animal biopsies)
to create a three-dimensional model without damaging the original biological specimen.
The mCT is used in the Department to examine the effects of various physiological conditions
(i.e., hormone or nutrient deficiencies) on bone microarchitecture. Specimens can
be scanned both in the absence of presence of solution (i.e., formalin fixative).
Departmental faculty members provide analytical services to other investigators across
campus to assess the structural and biomechanical properties of bone.
Faculty Contacts: Drs. Barbara Stoecker and Brenda Smith
Lunar Piximus: This pencil-beam DXA allows for the determination of bone mineral density and body
composition of small animal models (i.e., Mus musculus).
Faculty Contacts: Drs. Edralin Lucas and Brenda Smith
Perkin-Elmer Elan 9000 Inductively Coupled Plasma-Mass Spectrometer (ICP-MS): ICP-MS is a highly sensitive method useful for determining amounts of beneficial
or toxic trace elements that may be present only in the parts per billion range.
ICP-MS can be used for the elemental analysis of both biological (e.g., blood or urine)
and environmental (e.g., water) samples. The Department of Nutritional Sciences is
currently utilizing ICP-MS analysis to measure trace minerals in blood, serum, and
food, but it can also be used for mineral and isotope analyses of environmental samples
(e.g., water or soil samples).
Faculty Contact: Dr. Barbara Stoecker
For more general information regarding available equipment and services, please contact:
Department of Nutritional Sciences
415 Human Sciences